Authors: Hanchao Yu, Shanhui Sun, Haichao Yu, Xiao Chen, Honghui Shi, Thomas S. Huang, Terrence Chen Description: Motion estimation of cardiac MRI videos is crucial for the evaluation of human heart anatomy and function. Recent researches show promising results with deep learning-based methods. In clinical deployment, however, they suffer dramatic performance drops due to mismatched distributions between training and testing datasets, commonly encountered in the clinical environment. On the other hand, it is arguably impossible to collect all representative datasets and to train a universal tracker before deployment. In this context, we proposed a novel fast online adaptive learning (FOAL) framework: an online gradient descent based optimizer that is optimized by a meta-learner. The meta-learner enables the online optimizer to perform a fast and robust adaptation. We evaluated our method through extensive experiments on two public clinical datasets. The results showed the superior performance of FOAL in accuracy compared to the offline-trained tracking method. On average, the FOAL took only sh.4$ second per video for online optimization.