Model brittleness is a primary concern when deploying deep learning models in medical settings owing to inter-institution variations, like patient demographics and intra-institution variation, such as multiple scanner types. While simply training on the combined datasets is fraught with data privacy limitations, fine-tuning the model on subsequent institutions after training it on the original institution results in a decrease in performance on the original dataset, a phenomenon called catastrophic forgetting. In this paper, we investigate trade-off between model refinement and retention of previously learned knowledge and subsequently address catastrophic forgetting for the assessment of mammographic breast density. More specifically, we propose a simple yet effective approach, adapting Elastic weight consolidation (EWC) using the global batch normalization (BN) statistics of the original dataset. The results of this study provide guidance for the deployment of clinical deep learning models where continuous learning is needed for domain expansion.
Speakers: Sharut Gupta, Praveer Singh, Ken Chang, Mehak Aggarwal, Nishanth Arun, Liangqiong Qu, Katharina Hoebel, Jay Patel, Mishka Gidwani, Ashwin Vaswani, Daniel L Rubin, Jayashree Kalpathy-Cramer